Mexican drug lord Nemesio Oseguera, commonly known as “El Mencho,” has been killed in a military operation, a government source familiar with the operation told Reuters on Sunday.
An ex-police officer, Oseguera was the shadowy leader of the powerful Jalisco New Generation Cartel (CJNG), an outfit that took its moniker from the western state of the same name that is home to Mexico’s second city, Guadalajara.
Over a relatively short period of time, the CJNG morphed into a continents-spanning criminal enterprise rivaling his former allies in the Sinaloa Cartel, the gang of captured kingpin Joaquin ‘El Chapo’ Guzman, now in a U.S. prison.
The news of Oseguera’s death followed a federal security operation in the state of Jalisco’s city of Tapalpa, according to a post by governor Pablo Lemus Navarro on X.
After the operation, multiple vehicles were set on fire throughout Jalisco and other states, according to media outlets and officials.
Alfredo Ramirez Bedolla, the governor of the state of Michoacan, wrote on X that he had received reports of state highways being blocked as a result of the operation in Jalisco.
Oseguera’s death comes as the Trump administration has ratcheted up the fight against drug cartels and distributors in the western hemisphere. The United States, under Operation Southern Spear, has killed approximately 145 suspected drug runners in 42 strikes in the Pacific and Caribbean since September of 2025.
In January, the United States executed an operation to capture Venezuelan dictator Nicolás Maduro and his wife. The operation was considered extremely successful, with zero U.S. military fatalities, according to the Trump administration. The raid also featured a weapon President Trump described as the “discombobulator,” which allegedly “made [enemy] equipment not work.” The president said he couldn’t go into further detail on the weapon.
Additionally, Oseguera’s death follows the capture of Ovidio Guzmán López, the son of infamous drug trafficker El Chapo, in 2023 by Mexican authorities. Guzmán López was eventually extradited to the United States to stand trial where he pleaded guilty to drug charges, according to the Department of Justice.
“The Sinaloa Cartel is a terrorist organization that has spent decades destroying American families through brutal violence and deadly drug trafficking,” said Attorney General Pam Bondi. “[The] guilty plea from El Chapo’s son is a major victory against the Sinaloa Cartel and underscores the Trump Administration’s historic, aggressive campaign to dismantle terrorist organizations that target the American people.”
(Reporting by Emily Green and Lizbeth Diaz; Editing by Christian Plumb)
