Vaccine chiefs in the UK have suspended a newly approved jab from being given to people over 65, after reports of two deaths and 21 severe reactions.

The vaccine is supposed to protect against the potentially fatal Chikungunya virus, which is found in the subtropical regions of the Americas, Africa, Southeast Asia, India, the Pacific Region and increasingly in Europe.

Although the virus isn’t found in the UK, people can become infected while overseas and fall ill when they return home. 

The Mail Online reports: While the jab, called IXCHIQ, is approved in the UK it has yet to be rolled out, so there are no immediate safety concerns, British regulators said.  

The suspension follows global reports of 23 serious adverse effects in older people, including two deaths.

It followed two fatalities in the French island La Réunion—in the Indian Ocean—where a vaccination campaign is underway following a recent Chikungunya outbreak.

One death involved an 84-year-old man who developed encephalitis—a swelling of the brain—after having an adverse reaction to the vaccine. 

The other was a 77-year-old man living with Parkinson’s disease who reportedly began finding swallowing increasingly difficult after the jab. 

This is believed to have triggered aspiration pneumonia, a serious infection caused by food, saliva and/or vomit entering the lungs rather than the stomach.

The European Medicines Agency, who are reviewing the chikungunya vaccine following the reports, has not yet revealed the time between the dead men receiving the jabs and their deaths.

There are no changes in the recommendations for vaccination with IXCHIQ for people aged between 18 and 64.

The vaccine is currently not approved for use in individuals with a weakened immune system as a result of disease or medical therapy. 

The decision by the Commission on Human Medicines (CHM) is a precautionary measure until a further safety review has been concluded.

The Medicines and Healthcare products Regulatory Agency (MHRA) is working with the vaccine manufacturer Valneva.

The majority of people infected with Chikungunya develop a sudden fever and severe pain in multiple joints.

Other symptoms may include headache, muscle pain, joint swelling, or rash. 

The virus is spread to humans by bites from infected mosquitoes, but cannot be passed from person-to-person. 

Symptoms typically resolve within 7 to 10 days, and most patients make a full recovery.

However, in some cases the joint pain and arthritis may persist for several months or even years.

Occasional cases of eye, neurological and heart complications have been reported, as well as gastrointestinal complaints.

A small number of people may develop a severe version of the disease, which can lead to multiple organ failure and death.

Severe symptoms and deaths are rare and usually occur in young babies or elderly people with coexisting health problems.