Dimethyl sulfoxide (DMSO) effectively treats many ailments, including strokes, tissue injuries, autoimmunity, and a myriad of skin diseases and challenging infections
DMSO’s unique properties also make it highly suited for both eliminating cancers and protecting the normal cells from cancer therapies
Hundreds of studies have shown DMSO can transform a wide range of cancerous cells back into normal cells — something very few other agents are capable of
DMSO strengthens the immune response to cancer and allows the immune system to recognize and permanently eliminate many different cancers that otherwise evade the immune system
DMSO is directly toxic to cancerous cells and greatly increases the potency of a wide range of natural and conventional anticancer agents. This both increases cure rates and allows lower chemotherapy doses, significantly reducing their toxicity
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DMSO is a naturally occurring substance that, when used correctly,1 safely, and rapidly improves a variety of conditions medicine struggles with — particularly chronic pain. For example, thousands of studies show DMSO treats a wide range of:
• Injuries such as sprains, concussions, burns, surgical incisions, and spinal cord injuries (discussed here).
• Strokes, paralysis, many neurological disorders (e.g., Down syndrome and dementia), and numerous circulatory disorders (e.g., Raynaud’s, varicose veins, or hemorrhoids), which were discussed here.
• Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), which was discussed here.
• Many autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).
• Head conditions including tinnitus, vision loss, dental problems, and sinusitis (discussed here).
• Internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).
• A wide range of skin conditions such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases (discussed here).
• Many challenging infections such as shingles, herpes, chronic ear or dental infections, and osteomyelitis (discussed here).
Sadly, once the FDA realized the extent to which DMSO would transform medicine, the agency made the decision to erase it from history. As a result, millions of patients who it helped and the thousands of studies on its therapeutic potential have been largely forgotten. Consider for example this 1980 60 Minutes program:
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Watch on X
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Fortunately, because DMSO is effective for a wide range of conditions, it’s caught on like wildfire over the last six months (e.g., I’ve already received over 2000 reports of remarkable responses to DMSO, many for a variety of “incurable conditions”2).
DMSO and Cancer
Because of the controversy surrounding DMSO, once its pioneers realized it also treated cancer, a decision was made to downplay this facet of DMSO as “unproven” cancer cures are always attacked by the medical system. As a result, DMSO’s anticancer properties still remain relatively unknown.
In the first part of this series, I presented dozens of studies that show DMSO effectively treats cancer pain (which is often very challenging to address) and dramatically reduces many of the complications experienced from radiation therapy and chemotherapy (as it selectively protects healthy cells from those agents).
Given how debilitating each of those can be for a cancer patient, it is remarkable DMSO has not been adopted for any of those applications, particularly since addressing those does not take business from the cancer industry (and if anything would make more patients want to undergo conventional cancer care).
Note: 65% of oncologists’ revenue comes from chemotherapy drugs3 (which coincidentally are by far the most profitable drug market4).
In this article, I will focus on how DMSO eliminates cancer.
Cancer Differentiation
At the start of life, the first cell can become anything, and as it divides, it becomes more specialized through a process called differentiation. This process is vital in medicine, especially with stem cells, which can replace damaged cells. Cancer, however, is a disease of dedifferentiation,5 in which normal cells lose their structure and begin dividing uncontrollably.6
As such, something that could differentiate cancer cells into normal cells would be immensely helpful in treating cancer. Unfortunately, conventional medicine only has one agent like that (all-trans retinoic acid which is only used for a fairly rare blood cancer7).
All of this began in 1971, when a virologist discovered that DMSO could induce differentiation in erythroleukemia cells at a 2% concentration, making most of them revert to normal cells.8 At higher concentrations, DMSO stopped growth and even killed cancerous cells (and was much less likely to kill mice than those injected with untreated cancer cells).
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Following this, she published a variety of studies that mapped out how this process occurred, which agents suppressed or enhanced it. She showed that the differentiating effect persisted long after DMSO was no longer present.9,10,11,12 Her work in erythroleukemia was then repeatedly replicated (e.g., I’ve reviewed 62 corroborating studies,13 along with 95 more for the related cancer acute myelogenous leukemia14).
Note: DMSO’s ability to differentiate leukemic cells was so well recognized that in 1992, it was selected for a microgravity experiment on the International Space Station.15
By 1983, it was recognized DMSO could differentiate 12 different cancer types,16 and now this differentiating capacity has been repeatedly shown for each of the following cancers:
• Blood cancers — Acute promyelocytic leukemia,17 chronic myeloid leukemia,18 cutaneous erythromyeloleukemia,19 hairy cell leukemia,20 histiocytic lymphoma,21 Non-Hodgkin lymphoma,22 T-cell leukemia,23 T-cell lymphoma24
• Organ cancers — Bladder,25 brain,26 breast,27 colon,28 esophageal,29 intestinal,30 kidney,31 liver,32lung,33 prostate,34 rectal,35 ovarian,36 stomach,37 thyroid38,39
• Other cancers — Embryonic carcinoma (into heart cells),40 fibrosarcoma,41 melanoma,42nasopharyngeal,43 rhabdomyosarcomas44
Collectively, these studies showed:
• DMSO normally differentiated the cancer (it was rare for me to find studies where it did not) and did so in a dose-dependent fashion (e.g., 0.5% to 2% was often used45). At higher concentrations (e.g., 1.5%), those changes were often permanent.46
• Cancer growth, proliferation, and survival in tandem frequently decreased. In parallel, key tumor suppressing genes increased (e.g., P21,47 PTEN,48 and RB49), many cancer genes were suppressed,50 and the cancer cells were weakened (e.g., with transient DNA strand breaks) or induced into programmed cell death.51,52
As such, I believe it quite likely that if more cancer cell lines or specific cancer proteins and genes were tested, DMSO would demonstrate anticancer properties in those areas too.
Note: DMSO has also been repeatedly shown to prevent potent carcinogens from causing cancer.53,54,55
Mechanisms of Differentiation
In addition to DMSO positively changing many factors associated with cancer (e.g., reducing cancer genes, increasing anticancer proteins and altering cancerous DNA) a few other mechanisms have also been identified by researchers.
First, tumor cells typically grow chaotically, but adding 1% to 2% DMSO led to a more organized structure resembling normal cells.56 Over four days DMSO caused melanoma cells to reorganize their cytoskeleton, halting their growth.57 Likewise, in another study, 1% DMSO significantly altered the cellular skeleton of melanoma cells but not regular cells:58
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DMSO also affects other structural aspects of cancer cells:
• It shifts the cell membrane’s transition temperature making it more gel-like59 (a trait shared with other cancer differentiating agents60).
• DMSO caused disordered and tightly packed cancer cells to rearrange them themselves into an ordered parallel orientation like that seen in non-cancerous tissues.61
Note: Polar solvents besides DMSO can also both cause these changes and induce cancer cell differentiation, suggesting this is a fundamental component of the differentiation process.62
• DMSO shrank the cytoplasm of cancerous cells by 23% over nine hours.63
• DMSO increased the negatively charged phospholipid content in cancer cell membranes,64enhancing fluidity and improving the cell’s zeta potential (a measure of its electrical charge that determines the tendency for things to clump together).
Collectively, many of these studies touch upon a longstanding observation that the transition to cancer is in part due to the electrical charges and the state of the water within the cells (e.g., it should be in an energy generating liquid crystalline state65 — something raising the membrane transition temperature promotes), which is a topic I have written more about here.
Additionally, DMSO also dissolves a barrier around cancer cells that prevented chemotherapy drugs from entering them66,67 and was found to make cytoskeleton target chemotherapies 30 to 1000 times more potent.68
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Note: DMSO also allows chemotherapy to pass through the blood-brain barrier so that otherwise unreachable brain cancers can be exposed to chemotherapy.69
Pleomorphism
One of the forgotten schools of medicine is that microorganisms can assume different shapes (morphologies) and that particular morphologies can be highly detrimental to health. For example, previous pioneers of forgotten alternative cancer therapies (e.g., Rife70 and Naessens71) believed these hard to detect organisms caused types of cancers, and as I showed here, they are also linked to many autoimmune conditions.72
A 1967 Russian study tested cancer patients for pleomorphic bacteria, isolating them from blood samples of patients and those around people who had died from cancer.73 They took 59 samples from 53 patients and 17 tumor samples, with most yielding pleomorphic bacteria, which due to their small size, were highly susceptible to DMSO.
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